A United Arab Emirates national, Mr Al Shamsi will be responsible for Etihad Airways' airport operations in Abu Dhabi.
Mr Al Shamsi has worked in the airline industry for more than 23 years - including positions with Emirates Airline and Gulf Air - joined Etihad as Assistant Head of Hub, based at Abu Dhabi Airport, in February 2010.
James Hogan, Etihad Airways' Chief Executive Officer, said: "Ali's extensive airline experience and knowledge of the region have proven invaluable since he joined us earlier this year.
"He was the natural choice to take on the Head of Hub position, the most senior Etihad role at our busiest airport, in the recent reorganisation of our global airport operations.""Ali's promotion is part of our strategy to attract and develop top Emirati talent from across the UAE for our key positions in our expanding network."